Insert the Pam from “The Office” “same picture” meme here.

Shit - you know what? You’re right. It’s been a while since I saw the video, and I had it mixed up in my mind with a similar video I saw of a guy doing a fecal transplant to fix his lactose intolerance. I went back to check the Thought Emporium video, and yeah - he used a retrovirus to introduce the E. coli lacZ gene into his small intestine’s brush border cells. That’s my bad; sorry about the misinfo. You’re also right that I could have easily looked it up, but I went from memory instead, and it was… unreliable.

Same. :'(

No - this was a targeted therapy that introduced new islet cells into the patient’s pancreas. If he had damaged or non-functioning insulin receptors, this therapy would not have benefitted him.

This is a different matter entirely. The person who runs that channel (I love that channel, btw) does not have functional genes to produce lactase (the enzyme that lyses the bonds in lactose). Either he can’t make any lactase, or he can only make insufficient quantities of it.

What he did was introduce lactase producing bacteria into his small intestine. This required him to kill off most of his gut flora and then repopulate it with compatible species, including some lactase producers. So it’s not exactly correct to say that he cured himself of lactose intolerance; he just got something to create lactase for him. He had to repeat the therapy years later because his gut flora changed over time (likely due to shifts in his diet), and the quantity of little lactase producing bacterial buddies living in his intestines declined.

This experiment was done on a type 2 diabetes patient. Type 2 diabetes is characterized by damaged islet cells due to a diet high in glucose / carbohydrates. Changing the diet won’t undo the damage, it will just not cause further damage. This patient had enteric neuronal stem cells (nerve tissue from the gut) extracted, and those extracted cells were induced to differentiate into pancreatic islet cells in vitro (in a lab). Once differentiated, they were transplanted back into the patient, and they were able to successfully implant into his pancreas and repair some of the damage his diet had caused.

If the patient had type 1 diabetes, this would not be an effective therapy, as the issue in type 1 diabetes is that the body’s own immune system attacks the cells. A similar approach has been tested for type 1 diabetes, and it has seen some success when combined with immune suppressant drugs to limit the damage caused by the autoimmune disorder.

Since this patient had type 2, however, theoretically he should not need additional therapy as long as he does not go back to a destructive diet or suffer trauma to his pancreas due to accidents.

Interestingly, this is one of the few times I agree with Trump on something - we both think MTG is a traitor. Of course, I think she’s a traitor because of her constantly working to undermine the constitution, while he thinks she’s a traitor because she didn’t vote how he wanted once.

True. “Carol of the Bells” goes hard. It sounds like you’re being chased down a dark alley by a serial killer.

Daylight Saving time, Donald Trump & his supporters, the US healthcare “system”, mosquitos, Christmas music, babies on airplanes, hangnails, bigotry and intolerance of other people’s cultures, and the Dutch.

I used to hope that, but these last couple of decades have brutally beten such optimism out of me.

Klingon. I would love to hear my cat yell about glory while attacking a random bit of lint he found on the ground.

Edit: I realize you said “human” language, but a human invented klingons and their language, so I’m saying it counts.

Ok, but it’s providing information to advertisers about your activity, right? When I click on something, Firefox sells that information. Whether you consider it “personal data” is irrelevant; it is data about me: my actions.

You seem to be pretty hell-bent on defending Mozilla here. You work for them or something? It really is very simple. They started out more idealistic, but then they realized that things are expensive and there’s money to be made, so they sold out a little. It happens.

This counts as a “sale” even though no actual identifying information about you was exchanged. They mention this in the paragraphs I attached, when they talk about data sent via OHTTP.

I mean… it should count as a sale, because it’s a sale. They are selling information about browsing habits for money. Regardless of whether they include identifying information, it is still personal data that they are selling. They removed that line from their FAQs because they changed their minds about selling personal data. It has fuck all to do with weird legal definitions. They promised they wouldn’t ever sell personal data, and then they were like “wellll…”

As an example, the California Consumer Privacy Act (CCPA) defines “sale” as the “selling, renting, releasing, disclosing, disseminating, making available, transferring, or otherwise communicating orally, in writing, or by electronic or other means, a consumer’s personal information by [a] business to another business or a third party” in exchange for “monetary” or “other valuable consideration.”

Yes. That is selling. If you exchange customer data for money or other valuables, that is the definition of “selling”.

“The president uses social media to make a point,” Johnson told reporters Monday. “He believes that he is a king and that any protest against him or his appointed officials is treason. In essence, he is a fucking traitor who never should have gotten elected the first time, let alone the second, and I and my colleagues are going to work to impeach him and remove him from office, just as soon as we take our tongues out of his asshole.”

– Mike Johnson, if he was slightly less of a toady piece of shit traitor.

Given that this guy wrote about a dream he had wherein his grandmother grabbed a fistful of her pubes and stroked his face with them while asking him to comment on how soft they were, I think we can rule out demonic attack. They may be the minions of Satan, but even demons would be like “bro, what the fuck?!?”

He looks like he was taking a shit in the dark and got an itch on his upper lip mid-wipe.

This kills the human.

Man, it pains me to agree with JD Vance on anything, but we really do have the lamest opposition party. All they’re good for is performative bullshit like this. We’ve got Gestapo black bagging people on the street and dragging them off to foreign torture prisons, and the best the Dems can do is mock Trump for wavering on tariffs. It’s truly fucking pathetic.

I’m really struggling to understand how this could have happened. It’s not like sailing ships are speed demons. The average speed for a sail ship is like 7 knots, or about 8 miles per hour. Let’s say this bad boy was getting a strong gust of wind and got up to like 15 knots; that’s still only 17 miles per hour. Bridges, such as the Brooklyn Bridge, typically don’t move. Also, their height above the waterline is part of the public record. You can look that shit up. I just did a google search on “brooklyn bridge height above waterline”, and it says 135 feet. Super simple, took literally 5 seconds.

If you are sailing a giant, slow ship through a waterway that has a very famous bridge covering it… how the fuck do you decide to do that without looking it up first? And as they were approaching, they could have been like: “Hmm. That bridge seems low. We should double check our figures, and then turn around maybe if it looks close”.

I just… the level of sheer incompetence on display here is fucking staggering.