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Cake day: June 25th, 2023

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  • Chemistry might not be much better. It’s because scientists generally assume that readers already know how to do the techniques, and so the only information they would care to provide are the ones that wouldn’t be considered obvious. Such as equipment brand, the name of the technique if there’s multiple techniques that do the same thing, or experiment-specific modifications to the technique.

    My understanding is that it’s a holdover from older times, when scientists were charged per word, and so methodology would be cut down to remove anything considered “general enough” knowledge


  • If you’re asking scientists about writing protocols, you clearly don’t know how scientific protocols work. If anything, scientists need to take lessons from recipe writers on how to write protocols. Scientific protocols are notoriously difficult to replicate.

    Here’s a burger recipe written like a scientific methodology:

    Raw beef patties (Carshire Butcher) were prepared on a grill (Grillman) according to manufacturer’s instructions. The burger was assembled with the prepared patties, burger bun (Lee Bakery), lettuce (Jordan Farms), American cheese (Cairn Dairy), and various toppings as necessary. Condiments were used where appropriate. Assembled burgers were served within 15 minutes of completion.




  • You seem to be confusing what you want with gender roles. Nobody said that men must make the first move. Many satisfying relationships start because women make the first move. But by consequence of the fact that you want a relationship, it naturally then follows that you’d have to make the first move.

    IMO using props is a poor move. Might get your foot in the door, but it’ll be obvious that your interest/commitment to the prop is not genuine. People can tell if you’re acting, so I would ignore any comment that tells you to imagine and act out a scenario - doubly so if you’re using a prop.

    The trick is to realize that a cold call almost never works. There is a very low chance that any one person you run into on the street is looking for a relationship, and an even lower chance that they’d be willing to bet on a stranger for that relationship. So you’re facing 2 filters that are lowering your chances that any one person you meet would want to get into a relationship with you.

    You can’t affect the first filter, but you can at least change the second filter - just don’t be a stranger. It’s easier said than done, but it’s possible with concerted effort. To put it bluntly: be amicable and be social. Put yourself in situations where you meet people, and befriend them. And you are by far more likely to run into a potential partner from the people you already know than in a public park. I don’t even mean to pretend to be friends - I mean actually be friends. Socializing has a compounding effect where the more you socialize, the more people you get introduced to. That’s also important because of the fact that you can’t affect the first filter. Clearing the first filter is really a numbers game, to simply know a lot of people.

    You’ll need to learn to maintain a social circle. Based on what I can tell, you seem to either be an introvert or have social anxiety. And honestly, I understand. I can’t say that the process will be easy or that it’s fair that extroverts have a leg up in the process, but the unfortunate reality is that society is built upon the assumption that people are social, and you have to play by those rules. The upshot is that more people are willing to be in a relationship than you’d think, and you don’t really have to expand your social circle that much or maintain it that well before you come across someone who agrees to be in a relationship with you.



  • To me, that sounds like it’ll create more issues than it’ll solve. Part of why it’s difficult to get rid of large journals is because people like the centralization. Even beyond the obvious pride aspect of getting into an exclusive journal, a big reason for having journals is that it is much easier to find relevant papers if they’re collected and catalogued into a small number of large repositories (ie, journals).

    Federation intrinsically has lower discoverability, and it is difficult enough to find relevant papers that you want. And due to decentralization, it is more difficult to separate out the troll articles from the serious ones. That doesn’t matter if federation is used for a social media platform or if it is used for peer-to-peer communication, but it seems to run counter to the purpose of publishing scientific articles.

    And that’s not counting the issues that you would have with the review process on a federated service



  • Man, I’m not even old, but reading this post makes me feel old. And I’m certainly on the younger side of the spectrum for those who use Lemmy

    There’s a lot of things to unpack here, so it makes sense for me to just list them out:

    • your boyfriend seems to have some manosphere-esque tendencies. To me, it seems like it’ll be important for you to talk about this with him. The manosphere teaches young men about false truths and causes them to interpret the world in unusual, misogynistic ways. I don’t currently see any indication that he’s solidly in the manosphere, but it sounds like he may be influenced by it. It will be important for him to acknowledge and refute those influences if he plans to have any form of satisfactory long-term relationship.
    • it’s not your fault for receiving unsolicited sexual messages. Both you and your boyfriend will need to acknowledge that fact.
    • building on the previous point, getting sent an unsolicited sexual message does not and should not damage your relationship with your boyfriend. It’s not like you cheated or broke his trust. It sounds like he may have some unclear expectations for you that are impossible to meet. I would guess that it ties back to the first point about him being influenced by the manosphere. In any case, this seems important to bring up to him.
    • it is definitely your fault for sending false nudes to other people. If/when you are approached with an offer that you don’t like, the appropriate response is to say no, not to scam the other person.
    • it may not be your fault for getting unsolicited messages, but from a purely practical perspective, there are certain things that you can do that either encourage or discourage that sort of behavior. It sounds like you perform some sort of gig that tends to encourage this behavior. If you do not wish to get these sorts of messages, it would be a good idea to reconsider whether you should continue doing this gig
    • it’s important to learn, truly learn, that a relationship partner is someone who adds on to your life, not someone who completes your life. If you believe that your boyfriend is the only good thing in your life, I would recommend that you consider that this opens you up for exploitation or abuse, either intentionally or unintentionally. It sounds like you are affirming his manosphere-esque tendencies instead of calling him out on it. This will lead to greater strife and friction in the future



  • It should also be mentioned that the two methods aren’t mutually exclusive, and there’s a ton of synergy between using the old ways (x-ray crystallography and cryo-em) and using the new way (AlphaFold). Because even when you measure the protein structure, the old ways only tell you the shape of the protein but not the skeletal structure of the protein (which is the actual important part), so to my knowledge, there’s a bit of finicking around to figure out how the protein folds into that shape. AlphaFold predicts how the protein folds, so you can cross reference that with the measured shape of the protein to better estimate where the protein skeleton is in the measured shape


  • Bad guys who aren’t misunderstood but aren’t bad. They occupy a niche mindspace in which they have a genuine and noble goal but their goal is mutually exclusive with the good guy’s goals (the Shadowlord from Nier Gestalt)

    Then, on the flip side, bad guys who know that they’re bad and revel in it (Jack Horner from Puss in Boots)

    Good guys who are good leaders. They have no superhuman abilities but their power is to bring out the best in others. They don’t beat the bad guys through sheer strength or being inspired by the power of friendship (which IMO is just the same thing), but they do so by strategically playing to people’s strengths (Senku from Dr. Stone)






  • I’d say upgrade GPU. Buying a GPU is awful but it’s by far the most directly responsible for gaming performance. I’d probably look for an RX 7600 or RTX 4060. Both of them should be around 300 dollars. Also be aware that games are starting to use more VRAM. Both of my recommendations above have 8 GB of VRAM, and that’s already not enough for some games. If you have the extra money, it’ll certainly be a good idea to spend a bit more to get a 16 GB card (or at minimum, a 12 GB card). Your best options there would probably be RX 7600XT or RTX 4060 Ti 16 GB. Both of those cards should be around the 400 dollar range.

    Second priority would be upgrading your storage drives to SSD. Upgrading to SSD’s should help with general snappiness, and plus they shouldn’t be that expensive at this time. That should be around 100 dollars for 1 TB of SSD, or 50 dollars for 500 GB.

    3rd priority is CPU. It’s fine, but you might gett CPU bottlenecked in certain scenarios (especially after getting a GPU upgrade). An R5 5600 would be a slot-in upgrade, so you can keep using your other parts. Last I checked (which admittedly was a while back), they’re a pretty good deal, at around 120 dollars.

    4th priority is RAM. I’d actually say 16 GB RAM is fine for now, but RAM (and especially DDR4 RAM) is super cheap so you might as well upgrade your RAM if you’ve got the money.


  • Pretty sure lunar effect is a real, scientifically confirmed thing, just known by a different name. Perhaps not the full moon specifically, but we do oscillate according to the moon phase. It’s called circalunar cycles. The name might sound familiar to circadian cycles because they both derive from the same word structure, ie circa-dia (“around a day”) and circa-lunar (“around a month”)

    At minimum, I’m quite surprised that Wikipedia lists this as a pseudoscience, because my impression has generally been that circadian researchers acknowledge circalunar cycles as a given


  • The other comments cover things pretty well, but I feel like I should also pitch in as well. I’m in my mid-20’s in a stable relationship of over 3 years (at least a part of which was long distance), so I could probably offer some more age-specific advice.

    I find that a lot of younger people (ie, people at or below my age) put a lot of undue emphasis on social media. Liking a post, not liking a post, follow, not follow, whatever. These are all contrivances. They are a game designed by social media companies to keep people doomscrolling on their platform. It’s important to see and really understand that it genuinely does not matter what someone does on social media. Your boyfriend seems not to have interacted with the Instagram model after he got with you. So that’s good right? If that’s what’s really important to you, then why does it matter if he still follows her?

    And even if we assume that he was still actively interacting with the model, that’s still fine. It’s important to know that there is a difference between attraction and love. Love is the very specific feeling of caring about the other person and wanting the best for them. Many younger people think that attraction and love are the same, and so a lot of drama gets started because neither side realizes that they’re mixing up their ideas of what a relationship should be like. One common issue to be aware of (and most relevant to this situation) is that being attracted to someone else is not love, and it’s not cheating. It is ok to find other people attractive, and likewise, you should not find it offensive if your boyfriend finds someone else attractive.

    I will also caution that many younger couples have this expectation that their partners should allow them to go through the other person’s phones. This is extremely toxic. Don’t do that. People have a right to their own private life, even when they are in a relationship. This applies to social media as well. You shouldn’t be looking through your boyfriend’s Instagram just because you want to see if he’s following anyone that you don’t like. Remember that a relationship is built on trust, and that means that you need to trust your boyfriend to be loyal.

    You might be thinking that if you shouldn’t look through people’s phones, then it’s really easy for your boyfriend to cheat for a long time without you knowing. And that’s true. That’s why cheating hurts so much. But that possibility doesn’t give you the permission to intrude on their privacy. Have faith in your boyfriend.

    Finally, practice open communication and mindfulness. I find that it can be quite difficult to identify what exactly is bothering you, and talking to your boyfriend about a vague sense of jealousy isn’t going to be productive at all. In fact, it’s probably going to get him defensive. When you’re angry, disappointed, upset, jealous, etc., it’s important to take some time to think things through yourself first. These negative feelings tend to result from the feeling that one of your personal rights was violated. If you’re angry or upset, which specific action caused it? Which of your personal rights was violated by that action? It is really important to identify this, since the difference between toxic behavior and valid anger is oftentimes just based on how valid the answers are to those questions. For instance, the “right to your boyfriend’s attention” is not a real right that you have, and so if you were to get angry that your boyfriend isn’t giving you enough attention, that would, in fact, be toxic behavior. And if you do have a right to be angry, then knowing which of your rights was violated makes it easy to prove your point, so there’s no downsides to this approach.